Aim: In this retrospective study, the efficacy of adjuvant chemotherapy and its contribution to prognosis
were investigated in patients diagnosed with different subgroups of ovarian carcinoma at stages 1e3.
Material and Method: Epithelial ovarian carcinoma cases treated at Ankara Oncology Training and
Research Hospital of Health Sciences University between January 2014 and May 2018 were retrospectively
Results: A total of 145 patients were diagnosed and treated for EOC during the study period. According to
histopathological subgroups, serous EOC was the most common (84.8%), followed by endometrioid
(6.6%), mucinous (4.8%) and clear cell types (3.8%). Local recurrence and distant recurrences were
observed in 39 (43.8%) and 7 (7.9%) cases in the serous EOC group, respectively. The median follow-up
was 39 months (10e217 months). Median survival was 91.4 months (58.9e123.9 months) in the
whole group and 100.9 months in serous EOC. Median survival in mucinous EOC was 26.2 months,
whereas median survival in endometrioid EOC and clear cell EOC were not reached. A statistically significant
difference of survival was found between serous and mucinous types of tumors (p: 0.04.
Conclusions: According to the results of this study examining the survival outcomes of epithelial ovarian
cancer subtypes after chemotherapy, there was a statistically significant difference between the prognosis
of different epithelial ovarian cancer cases after taxane and platinum-containing adjuvant
chemotherapy. Mucinous type of tumors exhibited less overall survival compared to endometrioid and
clear cell types which needs to be confirmed with prospective clinical trials.