aDüzce University Faculty of Medicine, Department of Internal Medicine, Düzce, Turkey
bDüzce University Faculty of Medicine, Department of Internal Medicine, Division of Haematology, Düzce, Turkey
cDüzce University Faculty of Medicine, Department of Internal Medicine, Division of Oncology, Düzce, Turkey
Doi: 10.1016/j.jons.2017.11.003 - Article's Language: EN
Malignant mesothelioma, primarily located in the pleura, is a locally aggressive tumor. Distant metastases are rarely seen and mostly diagnosed postmortem. We present the third malignant pleural mesothelioma (MPM) case in the literature with bone marrow metastasis. A 36-year-old male patient presented with pain at the right mediastinal area and 5 × 6cm mass on the right side of his chest. 18-FDG positron emission tomography (PET) scan showed local uptake at the pleura, regional lymph nodes and 5th rib. The tru-cut biopsy reported as sarcomatoid type MPM. Cisplatin-pemetrexed therapy was planned. His medical condition deteriorated after 2 months and multiple metastases to brain, liver, adrenal glands and bone marrow were detected. The patient was lost 4 months after he was diagnosed. Brain and bone marrow metastasis of MPM are rarely seen. Physicians should be careful about the rapid progression and unexpected metastases of MPM.