ORIGINAL RESEARCH ARTICLE
Risk factors for thrombosis risk in patients with cancer
Received Date : 23 Apr 2018
Accepted Date : 19 Sep 2018
Doi: 10.1016/j.jons.2018.09.001 - Article's Language: EN
Journal of Oncological Sciences 4 (2018) 130-133
Aim: To evaluate the factors associated with Deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) in cancer patients.
Materials and Methods: A total of 237 cancer patients who underwent lower extremity venous Doppler Ultrasonography (USG) and/or pulmonary computed tomography angiography (PCTA) were included. Patients’ demographic characteristics; chemotherapy data; immobilization status; use of central venous catheter; histories of 4-day-long bed rest, surgery within the last 6 months, long anesthesia for at least 2 hours, smoking, patients’ laboratory tests, ABO blood group, PCTA and lower extremity Doppler USG results were retrospectively reviewed through the hospital information management system.
Results: The median age was 62 (age range 25 to 89). Thrombosis was detected in 83 patients according to the results of venous Doppler USG and/or PCTA of those patients who underwent imaging. Immobilization status (p¼0.019), history of surgery within the last 6 months (p¼0.02), anesthesia more than 2 hours (p¼0.012) and 4-day-long bed rest (p¼0.03) were found to be significantly associated with related risk of thrombosis. Additionally, thrombosis was found more frequently in the non-O group (especially group B) than in O group (p:0.024).
Conclusions: Besides well-known risk factors, blood group may be related with risk of thrombosis in the patients with the cancer diagnosis
Keywords: ABO blood group; Cancer; Pulmonary thromboembolism; Deep vein thrombosis